The Anti-Helios Purified Antibody from MyBioSource.com is a Hamster Monoclonal antibody to IKZF2. This antibody recognizes Human, and Mouse antigen. The Anti-Helios Purified Antibody has been validated for the following applications: Flow Cytometry.
Description
Helios, also known as IKZF2 (Ikaros family zinc finger protein 2) is a hematopoietic-specific transcription factor involved in the regulation of lymphocyte development, together with other members of this family, such as Aiolos and Ikaros. Helios forms homo- and heterodimers with these proteins and is thought to function predominantly in early hematopoietic development. Expression of Helios, Aiolos and Ikaros is restricted to cells of the hematopoietic system, whereas other family members, Eos and Pegassus, are more widely expressed. Helios is expressed at early stages of thymocyte development. In mature T cells, Helios has been strongly associated with Treg cells